Stupid Viruses on Windows XP

[One_Divided]

Well it found 22 viruses in the end and I was able to delete all but 4... The 4 are running processes and when I try to close them, they re-open so I can't delete them.. Got any ideas?

The system that is infected is for work only and I barely go on the net with it at all other then to get drivers and updates.. I never check email on it..

Changing the OS is not an option as I have thousands of hours of clients work on here which will be non compatable otherwise..