New Tank

[Stevo]

I am currently in the process of designing my first saltwater aquarium, Tank and stand will both be constructed by myself. The tank measurements have been decided as 61"X21"X22"H. Out of 1/2 float glass. The frame of the stand will be constructed out of 2X4 wood studs. My question is for the bottom base would i be able to use 2X2 wood studs for the perimeter frame?