I would have skimmer in the first chamber a fuge In the second chamber and leave the last empty so there is less chance of a bunch of micro bubbles going into your tank. this also allows for the ditris that is missed by your skimmer to settle out of the water column. I am working on a sump that has a maze in it this lengthens the distance the water has to flow before it exits the sump. I will be building some egg crate channels that will sit in the maze for sponges and feather dusters to attach to so they will Polish the water more than the skimmer will.

Bill