Its usually the first couple days of being introduced into a new tank that the old fish are most aggressive. I found in the past that when introducing new tangs into a tank full of tangs, the isolation chamber helped get the old fish "used" to the new fish. I've also had to return some new fish to the LFS if the old fish remained relentlessly aggressive, even several days later. Saved a lot of unnecessary wear and tear on the new fish (important if you expect the LFS to take it back). It also saved me having to tear down my tank to catch out the victim.
I admittedly haven't used it in a few years, but now I have a big Sohal so my urge to add a lot of tangs into the tank is very much tempered.
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