The powerheads would have to be dipped in something pretty nasty to cause that much chaos. Diluted to a full tank system, it would have to be something VERY strong to cause something like this. Try looking at other causes, what are your nitrates at? nitrates will strip oxygen from the water faster than anything if they get out of control. You said your skimmer is not hooked up? what are you using for filtration currently? it that leeching nitrates back to the tank?
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