I've got a friend who makes quite a few acrylic tanks...
As long as you're careful, they don't scratch TOO easily and they can be buffed out. They are lighter, more durable and less likely to break (think rockslide), plus they don't have that green tint that thicker glass does. However, it is not cost effective to even bother with acrylic unless doing a very large tank as cell cast acrylic can be $$$
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