If you are building a tank, for the outer glass you need structural silicone. The stuff from big box stores is a sealant, not a construction silicone adhesive. For baffles and stuff like that, the cheap stuff is fine (as long as it does not have any antibacterial or antifungal additives). But for building a tank, you gotta use something like GE1200 that has a high shear rating.
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