Initial thoughts are Flukes, primarily due to the rapid breathing. Other symptoms might include redenning of skin, flashing and sunken belly. Try a freshwater dip (same temperature & pH as aquarium water) for 5-10 minutes. Osmotic shock will cause most parasites to detach its host. If there is a heavy infestaion, do not dip too long as it can cause additional damage to the Grouper. Return the fish to your aquarium and check the freshwater container for small, translucent flat parasites. If you find Flukes or other Trematode parasites, you may need to treat the entire system with a product called Prazi-Pro.
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