I have water go stagnant but i don't think stale if you keep it slightly agitated. The biggest problem is keeping bugs and stuff out of the water. I assume that bacteria would form on water that sat for an extended period. I usually make 50 gallons at a tie and it sits being agitated for a few weeks and never have problems.
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360 gallon sps reef, 180 gal sump, bubble king supermarine 300, 4xmp40Wes, 2 x 6215 tunze waveboxes, 4 ghl mitras
360 Reef Tank
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