Going on vacation sucks, it is nerve racking for sure!
I use an autofeeder. I fill a larger rubbermaid tote with enough RO for the duration of the leave. I make sure all of my equipment has been cleaned. I place a powerhead on battery backup. Murphy told me that if something is going to fail it is going to fail while you're on vacation. I have a family member or a friend pop in once every other day or so to check and make sure there is still water in the tank and not on the floor.