Start on a bike at the gym. It will be a bit easier on you when you begin. Once your able to bike on a med-hard level for 30-40min straight move over to some running machines.
If you have alot of issues with your knees, start taking Glucosamine to help with your knees. You won't notice any effect but it will help strengthen your joints allowing your knees to take the pressure while running. I have messed up knee's and running on machines seems to be a bit easier on me. Hopefully next spring I can get outside and run but for now I find the impact on my knees to be to painful while running on concrete.
For me, I drink a thick whey protein shake before and after. I hate running on an empty stomack, makes me feel light headed and sick.
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