The biggest downside of the Aquamedic reactor (I have run one with great success) is that if you don't have an ORP controller or at least an ORP monitor that you're nearly constantly checking and fiddling with flow rate, then your anaerobic culture will start to produce acidic outflow, as someone as already pointed out. At best, this lowers your pH, at worst it kills everything in your tank if you're not there to make adjustments for a while. And I've had everything happen to me with that unit before I got the ORP controller. In the end, I did like it and acieved great success with it at maintaining 0 nitrates but the bad ca definitely outweigh the good if it used without the proper care.
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