Since you mentioned a SPS Dominated tank, I'm curious which softies/lps you are looking to keep...
2 MP20's would be 44x turnover + your return from the sump.
2 MP40's would be 71x turnover + your return from the sump.
That's only of course if you are running them at 100%.. I think closed loops are great, I got one myself, but I just got my hands on a MP20, and I gotta admit, it is a sweet piece of kit!
For you tank I would probably go with 2 MP20's plus your sump return. Only because you might have softies/lps... if it was 100% SPS, I'd recommend the 2x MP40 route.
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