As Indonesia and Sri Lanka were the 2 largest hit areas, I've donated to the Canadian Association for United Sri Lanka already and am next considering to donate directly to the Indonesian Embassy
http://www.indonesia-ottawa.org/ unless I can find a better Indonesian organization.
After that, I'm also donating to one of the global organizations like Red Cross where the gov't and my employer will match 1 for 1 so essentially, its like getting $3 for the price of $1 before Jan 11th. Although its not clear how much of that donation Red Cross will allocate directly to the Tsunami relief vs other humanitarian projects.