I have a very accurate scale. Each 23mg pill weighs .95mg so I have a record of exactly how much I have been adding.

Todays dose will be the 5th treatment. I have an exact breakdown of what was added and when I added based on the size of my tank. As soon as I am confident I have the right dose I will let you all know what that dose is. Even though I know I go go up to 4 times the recommended amount I do not want to go there unless I have to as I do not want to kill more microfauna then I have to.

My last dose was 43mg which is almost half a tablet. 1 tablet is supposed to treat 400 gallons per treatment. My tank is about 75-80 gallons of actual water so I should be using 19mg per treatment. At 43mg I was using 2.4 times the recommended dose.

I will be adding about 50-55mg (of a tablet) later today which would be 2.7 times the recommended dose. I have to take my skimmer offline and remove my carbon. I use no other form of filtration like GFO, carbon dosing ect. It is a good thing there are 8 tablets in a package I may end up needing them all.

What I do not know is:
How will the other treatments affect this treatment?
Does the drug build up in the system?
Does the black bug build up a resistance with the lower doses?
Does skimming and carbon remove residual drug from the water?

What I will be able to do is establish a baseline from which other reefers can treat their tanks.

I just made the last dose (I hope) at .54mg of a pill. That works out to 2.8 times the recommended dose for red bug.

A couple things to note. This pill does not dissolve in water. I use a pestle and mortar to crush the pill up into a fine dust. I then mix that with a cup of RO water for about a half hour. After a half hour there is still fines that have accumulated on the side cup. I mush these with my finger (where gloves) until the fines have disappeared. I want to be sure to that all of the drug gets into the water and I do not waste any that hasn't fully dissolved.

Since I have been adding this drug to my tank film algae is growing at an exponential rate nearly 3 times faster then before on the glass.

Let them have it Glen nuke em!
8pk of pills that is nice my vet sold me a dose 1 pill only. That came in a box marked large dog.

After your findings I’ll let my vet read your write up and I’m sure he will be more prone to prescribe multiple pills to a reefers for a treatment of there tank . Your thread is much better than all out so far .
Thank you

My mistake there are 6 in a box of Interceptor Flavor Tabs Large dog not 8. I have used 2 so far for my 75 gallon tank.

It is raining bristle worms in my tank. Looks like I have hit the Bristle worm threshold.

Ok it is Thursday night, my last dose was last Saturday and it is time for an update. I have been keeping a close eye on my corals looking at them closely every night and have not seen any activity. This evening I broke out the microscope and did a complete full view of my orange passion.

These little guys are really small and even with a microscope they are tough to find. They are smaller then the tip of a polyp and often hide inside the coralites making them tough to see. Tonight when I pulled out the orange passion the polyps were out a lot more than usual and seemed really big. I took me about a hour to completely search the coral. A couple of times my heart stopped because I thought I saw a black bug, however it was usually just a polyp at an odd angle. I could find no black bugs. I also pulled out a coral from my quarantine tank to give it a once over and found no black bugs.

I am going to call this a success for now and will keep you posted. It took me 5 treatments to finally get this guy. One pill is 94mg (23mg of actual drug) First 2 treatments were 20mg (1/5th) of a pill. The third treatment was 31mg, the forth treatment was 43mg and the final treatment was 54mg more than half a pill. I ended up using almost 2 whole pills for my 75 to 80 gallons of actual water. The drug I used was Interceptor Flavor Tabs as it has only Milbemycin Oxime and nothing else. I was a little worried about Sentinel or the other ones because they have other drugs. I was using fresh Interceptor expiry date Jan 2021. So there shouldn't have been a problem with drug potency.

The Good
I watch my corals closely and am always aware the first sign that something is wrong. Many of my acros currently look better than they have in a very long time. They are showing colours I have not seen and polyps are extended during the day. I feel I may be over the hump with this pest. The treatment did not effect any of my fish or corals and I am not sure about the snails because I had hundreds and I still have many.
The Bad
The drug is expensive and difficult to get. I have pretty much wiped out my pod, my bristle worm and my feather duster populations. Some would consider loss of bristle worms as a good thing, I do not follow that chain of thinking. CUC can be replaced. It took a while to get this drug to work. Coral dips like Coral Rx are not effective on this bug.
The Ugly
This pest is extremely difficult to detect. I have had this pest for a long time and it has effected many of my acros, I can't say they directly killed them but they stressed them. I am hoping that local reefers will really inspect their acros because if they do not they will just keep being spread to reefers tanks.

Great write up frogger! Hope I don’t get these buggers, but if I do I can refer to this.

THE KILLING DOSE
I have calculated out the dosage that seemed to kill the black bugs and it is nearly 3 times the recommended dose for red bugs.

One 23mg tablet will treat 135 gallons of water.
3/4 of a tablet will treat a 100 gallon tank. This works out to 16.7mg of Milbemycin Oxime per 100 gallons. One tablet is 23mg (M.Oxime) and weighs 94mg.

As I did 5 doses I do not know if the earlier doses played any part in killing all of these bugs. You might have to do multiple treatments.

I make no promises that you will have the same success as me, it may wipe out your entire tank. I have no shrimp, crabs or clams in my tank so I do not know how these would be affected, based on the red bug treatments probably not well.

Thanks for the up date ! Keeping my fingers crossed for you . Hope you got them all .