The instructions recommend something called the 'bomb' method, which is putting them in a bag with an air stone so that they're constantly surrounded by high flow and turbulent bubbles. People who have not been able to successfully implement this method have reported less success with them in terms of nitrate reduction.

There's drawback to the bomb method, such as getting it to work without the bag and air stone floating above most of the pellets and the salt creep the bubbles will produce. My tank has durso style overflows, which produce a hurricane's worth of bubbles, so I just put the bag in the my filter sock and have a custom cut piece of foam sitting on top to limit salt spray, and it seems to work fine.

Thanks for the info guys! I think I'll try out the Nutriguard cube bomb and see how she goes.